Specification
Entrez GeneID | 920 |
Aliases | CD4mut; CD4 |
Clone# | B486A1 |
Host/Isotype | Mouse IgG1 |
Storage | 4℃; -20℃ for long term storage. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human CD4 expressed in E. Coli. |
Formulation | Ascitic fluid containing 0.03% sodium azide. |
Application
ELISA | 1/10000 |
Description
The CD4 antigen is highly expressed on human T helper cells and thymocytes, and at lower levels on
monocytes and dendritic cells. This integral membrane glycoprotein of approximately 58 kDa contains four external domains (D1 to D4) that show homology to members of the immunoglobulin (Ig)
superfamily. It is responsible for the recognition of the MHC class II antigen. The CD4 antibody
recognizes most thymocytes and about 65% of peripheral blood T cells.
monocytes and dendritic cells. This integral membrane glycoprotein of approximately 58 kDa contains four external domains (D1 to D4) that show homology to members of the immunoglobulin (Ig)
superfamily. It is responsible for the recognition of the MHC class II antigen. The CD4 antibody
recognizes most thymocytes and about 65% of peripheral blood T cells.
References
1. M Benkirane J Virol. 1995 November; 69(11): 6898-6903.
Diagram