CD8
图片
- Flow cytometric
Flow cytometric analysis of blood T cells using CD8 mouse mAb (M2) and negative control (M1).
Mouse Antibody to CD8
Catalog#
: 20008
| Size/Concentration： | 50ul | 100μl | |
| Price:￥ | 1280 | 2180 |
Instruction: 
Specification
| Entrez GeneID | 925 |
| Aliases | MAL; p32; Leu2; CD8A |
| Clone# | RAVB3 |
| Host/Isotype | Mouse IgG1 |
| Storage | 4℃; -20℃ for long term storage. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human CD8 expressed in E. Coli. |
| Formulation | Purified antibody in PBS containing 0.03% sodium azide. |
Application
| ELISA | 1/10000 |
| FCM | 1/200 - 1/400 |
Description
CD8 T cell surface antigen is heterodimer of an alpha and a beta chain linked by two disulfide bonds .It belongs type I membrane protein. Selectively expressing of CD8 on a subset of T cells leads to CD8 T cell development. Through identifying cytotoxic/suppressor T-cells that interact with MHC class I bearing targets, CD8 is thought to play a role in the process of T-cell mediated killing. Veillette et al (1988) found the CD8 is associated with the internal membrane tyrosine-protein kinase p56lck.
References
1. Veillette, A. et al. 1988. Cell 55:301.
Diagram
| Flow cytometric |
Flow cytometric analysis of blood T cells using CD8 mouse mAb (M2) and negative control (M1). |