CD4
图片
- Flow cytometric
Flow cytometric analysis of blood T cells using CD4 mouse mAb (M2) and negative control (M1).
Flow cytometricFlow cytometric analysis of PBMC cells using CD4 mouse mAb (green) and negative control (blue).
Mouse Antibody to CD4
Catalog#
: 20007
| Size/Concentration： | 50ul | 100μl | |
| Price:￥ | 1280 | 2180 |
Instruction: 
Specification
| Entrez GeneID | 920 |
| Aliases | CD4mut |
| Clone# | B486A1 |
| Host/Isotype | Mouse IgG1 |
| Storage | 4℃; -20℃ for long term storage. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human CD4 expressed in E. Coli. |
| Formulation | Purified antibody in PBS containing 0.03% sodium azide. |
Application
| ELISA | 1/10000 |
| FCM | 1/200 - 1/400 |
Description
The CD4 antigen is highly expressed on human T helper cells and thymocytes, and at lower levels on monocytes and dendritic cells. This integral membrane glycoprotein of approximately 58 kDa contains four external domains (D1 to D4) that show homology to members of the immunoglobulin (Ig) superfamily. It is responsible for the recognition of the MHC class II antigen. The CD4 antibody recognizes most thymocytes and about 65% of peripheral blood T cells.
References
1. M Benkirane J Virol. 1995 November; 69(11): 6898-6903.
Diagram
| Flow cytometric |
Flow cytometric analysis of blood T cells using CD4 mouse mAb (M2) and negative control (M1). |
| Flow cytometric |
Flow cytometric analysis of PBMC cells using CD4 mouse mAb (green) and negative control (blue). |