CD3
图片
- Immunofluorescence
Immunofluorescence analysis of peripheral blood T cells using CD3 mouse mAb (A) and flow cytometric analysis of eripheral blood T cells using CD3 mouse mAb (B).
Mouse Antibody to CD3
Catalog#
: 20037
| Size/Concentration： | 50ul | 100μl | |
| Price:￥ | 1280 | 2180 |
Instruction: 
Specification
| Entrez GeneID | 919 |
| Aliases | T3Z; CD3H; CD3Q; CD3Z; TCRZ; CD3-ZETA; CD247 |
| Clone# | 4D10A6 |
| Host/Isotype | Mouse IgG2a |
| Storage | 4℃; -20℃ for long term storage. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human CD3 expressed in E. Coli. |
| Formulation | Purified antibody in PBS containing 0.03% sodium azide. |
Application
| ELISA | 1/10000 |
| ICC | 1/200 - 1/1000 |
Description
CD3 is a component of T cell surface receptor (TCR), it cantains 5 invariable chains: gamma- , delta-, epsilon-, and zeta/eta?Clevers et al. (1988) showed the TCR/CD3 complex consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits,CD3 is responsible for the signal transduction of the TCR.
References
1. Clevers, H. Annu. Rev. 1988. Immun. 6: 629-662.
Diagram
| Immunofluorescence |
Immunofluorescence analysis of peripheral blood T cells using CD3 mouse mAb (A) and flow cytometric analysis of eripheral blood T cells using CD3 mouse mAb (B). |