Specification
Entrez GeneID | 919 |
Aliases | T3Z; CD247 |
Clone# | 4D10A6 |
Host/Isotype | Mouse IgG2a |
Storage | 4℃; -20℃ for long term storage. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human CD3 expressed in E. Coli. |
Formulation | Ascitic fluid containing 0.03% sodium azide. |
Application
ELISA | 1/10000 |
FCM | 1/200 - 1/400 |
Description
CD3 is a component of T cell surface receptor (TCR), it cantains 5 invariable chains: gamma- , delta-, epsilon-, and zeta/eta?Clevers et al. (1988) showed the TCR/CD3 complex consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits,CD3 is responsible for the signal transduction of the TCR.
References
1. Clevers,H.Annu.Rev.Immun.6:629-662,1988.
Diagram
Flow cytometric |
FCM analysis CD3 expressed in human peripheral blood cells. |