CD19
图片
- Immunohistochemistry
Immunohistochemical analysis of paraffin-embedded human normal lymph node, showing cytoplasmic localization using CD19 mouse mAb with DAB staining.
Mouse Antibody to CD19
Catalog#
: 20028
| Size/Concentration： | 50ul | 100μl | |
| Price:￥ | 1280 | 2180 |
Instruction: 
Specification
| Entrez GeneID | 930 |
| Aliases | B4; MGC12802 |
| Clone# | 2E2B6B10 |
| Host/Isotype | Mouse IgG2b |
| Storage | 4℃; -20℃ for long term storage. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human CD19 expressed in E. Coli. |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
Application
| ELISA | 1/10000 |
| IHC | 1/200 - 1/1000 |
Description
The CD19 antigen (95kDa) is expressed from the earliest stage of B progenitor development, on all
peripheral B cells including germinal centre B cells, and all B cell lines and B cell leukaemia
tested. T cell and monocytic cell lines are negative and the antigen is lost on B cell maturation
to plasma cells. The antigen is a type I integral membrane glycoprotein whose in vitro inhibition
will influence B cell activation and proliferation.
peripheral B cells including germinal centre B cells, and all B cell lines and B cell leukaemia
tested. T cell and monocytic cell lines are negative and the antigen is lost on B cell maturation
to plasma cells. The antigen is a type I integral membrane glycoprotein whose in vitro inhibition
will influence B cell activation and proliferation.
References
1. Rie, M.A. de, J. of Immunol. Methods, 1987. 102: 187.
2. Rie, M.A. de, Leukaemia Research, 1988. 12: 135.
2. Rie, M.A. de, Leukaemia Research, 1988. 12: 135.
Sequence
226-241 LSLELKDDRPARDMW
Diagram
| Immunohistochemistry |
Immunohistochemical analysis of paraffin-embedded human normal lymph node, showing cytoplasmic localization using CD19 mouse mAb with DAB staining. |