CD14
图片
- Flow cytometric
Flow cytometric analysis of human PBMC using CD14 mouse mAb.
ImmunohistochemistryImmunohistochemical analysis of paraffin-embedded human lymphnode, showing membrane localization using CD14 mouse mAb with DAB staining.
Mouse Antibody to CD14
Catalog#
: 20020
| Size/Concentration： | 50ul | 100μl | |
| Price:￥ | 1280 | 2180 |
Instruction: 
Specification
| Entrez GeneID | 929 |
| Aliases | CD14 |
| Clone# | 5A3 |
| Host/Isotype | Mouse IgG1 |
| Storage | 4℃; -20℃ for long term storage. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human CD14 expressed in E. Coli. |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
Application
| ELISA | 1/10000 |
| FCM | 1/200 - 1/400 |
| IHC | 1/200 - 1/1000 |
Description
CD14 antigen is a GPI-linked glycoprotein with a molecular weight of 55kD. The CD14 antigen is expressed on cells of the myelomonocytic lineage including monocytes, macrophages and Langerhans cells. Low expression is observed on neutrophils and on human B cells. CD14 antigen is a receptor for bacterial lipopolysaccharide (LPS, endotoxin) and the lipopolysaccharide binding protein (LBP). LBP and CD14 antigen serves two physiological roles. These proteins act as opsonin and opsonic receptor, respectively, to promote the phagocytic uptake of bacteria or LPScoated particles by macrophages.
References
1. J Mammary Gland Biol Neoplasia 2000, 5 : 227-241.
2. J Mammary Gland Biol Neoplasia 2000, 5 : 165-185.
2. J Mammary Gland Biol Neoplasia 2000, 5 : 165-185.
Sequence
23-327
Diagram
| Flow cytometric |
Flow cytometric analysis of human PBMC using CD14 mouse mAb. |
| Immunohistochemistry |
Immunohistochemical analysis of paraffin-embedded human lymphnode, showing membrane localization using CD14 mouse mAb with DAB staining. |