Mouse Antibody to IL-1a
Catalog#
: 20010
| Size/Concentration： | 50ul | 100μl | |
| Price:￥ | 1280 | 2180 |
Instruction: 
Specification
| Entrez GeneID | 3552 |
| Aliases | IL1; IL-1A; IL1F1; IL1-ALPHA |
| Clone# | 3A6F11 |
| MW | 30.6kDa |
| Host/Isotype | Mouse IgG2a |
| Storage | 4℃; -20℃ for long term storage. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human IL1a expressed in E. Coli. |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
Application
| ELISA | 1/10000 |
Description
Interleukin-1alpha is a member of the interleukin 1 cytokine family. It is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease
References
1. Du,Y.; et al. 2000. Neurology 55: 480-484.
2. Grimaldi, L. et al. Ann. Neurol. 47: 361-365, 2000.
2. Grimaldi, L. et al. Ann. Neurol. 47: 361-365, 2000.
Diagram