Mouse Antibody to IL-16
Catalog#
: 20012
| Size/Concentration： | 50ul | 100μl | |
| Price:￥ | 1280 | 2180 |
Instruction: 
Specification
| Entrez GeneID | 3603 |
| Aliases | IL16 |
| Clone# | 5D8 |
| Host/Isotype | Mouse IgG1 |
| Storage | 4℃; -20℃ for long term storage. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human IL-16 expressed in E. Coli. |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
Application
| ELISA | 1/10000 |
Description
Interleukin-16, also known as lymphocyte chemoattractant factor (LCF), is a chemotactic cytokine that stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils through binding to the CD4 receptor . IL-16 induces human T-lymphocyte expression of interleukin 2 receptor and upregurates major histocompatibility complex ?molecules on resting human T lymphocyte. It is able to render CD4+ T cells unresponsive to TCR/CD3 stimuli. Moreover, IL-16 inhibits the replication of T cell and monocyte tropic HIV strains in vitro.
References
1. Cruikshank, W.W. et al 1994. Proc. Nat. Acad. Sci. 91: 5109-5113.
Diagram