BCL2
图片
- Elisa
Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Flow cytometricFlow cytometric analysis of THP-1 cells using BCL2 mouse mAb (green) and negative control (red).
Mouse Antibody to BCL2
Catalog#
: 32188
| Size/Concentration： | 50ul | 100ul | |
| Price:￥ | 1280 | 2180 |
Instruction: 
Specification
| Entrez GeneID | 596 |
| Aliases | Bcl-2; PPP1R50 |
| Clone# | 3F3F2 |
| MW | 26.3kDa |
| Host/Isotype | Mouse IgG1 |
| Storage | 4℃; -20℃ for long term storage. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human BCL2 (AA: 1-239) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application
| ELISA | 1/10000 |
| FCM | 1/200 - 1/400 |
Description
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.
References
1.J Immunother Cancer. 2020 Apr;8(1):e000489.
2.Pathol Res Pract. 2019 Aug;215(8):152477.
2.Pathol Res Pract. 2019 Aug;215(8):152477.
Sequence
1-239
Diagram
| Elisa |
Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) |
| Flow cytometric |
Flow cytometric analysis of THP-1 cells using BCL2 mouse mAb (green) and negative control (red). |