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GZMK

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
  • Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
  • Flow cytometric analysis of Jurkat cells using GZMK mouse mAb (green) and negative control (red).
  • Flow cytometric analysis of MOLT4 cells using GZMK mouse mAb (green) and negative control (red).
  • Immunohistochemical analysis of paraffin-embedded human tonsil tissues using GZMK mouse mAb with DAB staining.

图片

  • Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

  • Flow cytometric analysis of Jurkat cells using GZMK mouse mAb (green) and negative control (red).

  • Flow cytometric analysis of MOLT4 cells using GZMK mouse mAb (green) and negative control (red).

  • Immunohistochemical analysis of paraffin-embedded human tonsil tissues using GZMK mouse mAb with DAB staining.

Mouse Antibody to GZMK
Catalog#   :  32147
Size/Concentration: 50ul100ul
Price: 12802180
Instruction:
Specification
Entrez GeneID3003
AliasesTRYP2
Clone#5B4A5
MW29kDa
Host/IsotypeMouse IgG2b
Storage4℃; -20℃ for long term storage. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenPurified recombinant fragment of human GZMK (AA: 27-264) expressed in E. Coli.
FormulationPurified antibody in PBS with 0.05% sodium azide
Application
ELISA1/10000
FCM1/200 - 1/400
IHC1/200 - 1/1000
Description

This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes.

References
1,Brain. 2019 Nov 1;142(11):3411-3427.
2,J Invest Dermatol. 2019 Apr;139(4):930-939.
Sequence

27-264


Diagram
Elisa

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Flow cytometric

Flow cytometric analysis of Jurkat cells using GZMK mouse mAb (green) and negative control (red).

Flow cytometric

Flow cytometric analysis of MOLT4 cells using GZMK mouse mAb (green) and negative control (red).

 

Immunohistochemistry

Immunohistochemical analysis of paraffin-embedded human tonsil tissues using GZMK mouse mAb with DAB staining.

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