GPR19
图片
- Elisa
Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Flow cytometricFlow cytometric analysis of C6 cells using GPR19 mouse mAb (green) and negative control (red).
Mouse Antibody to GPR19
Catalog#
: 32133
| Size/Concentration： | 50ul | 100ul | |
| Price:￥ | 1280 | 2180 |
Instruction: 
Specification
| Entrez GeneID | 2842 |
| Clone# | 6A1D8 |
| MW | 47.6kDa |
| Host/Isotype | Mouse IgG2a |
| Storage | 4℃; -20℃ for long term storage. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human GPR19 expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application
| ELISA | 1/10000 |
| FCM | 1/200 - 1/400 |
Description
G protein-coupled receptors (GPCRs) is known to be involved in the pathogenesis of a variety of diseases, including cancer initiation and progression. Within this family, approximately 140 GPCRs have no known endogenous ligands and these orphan" GPCRs remain poorly characterized. The orphan GPCR GPR19 was identified and cloned 2 decades ago. its expression to be elevated in breast cancers may play a potential role in breast cancer pathology.
"References
1.Biochim Biophys Acta Mol Cell Res. 2017 Jul;1864(7):1318-1327.
2.Mol Cancer Res. 2012 Oct;10(10):1343-58.
2.Mol Cancer Res. 2012 Oct;10(10):1343-58.
Diagram
| Elisa |
Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) |
| Flow cytometric |
Flow cytometric analysis of C6 cells using GPR19 mouse mAb (green) and negative control (red). |