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ALK/p80

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
  • Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
  • Western blot analysis using ALK/p80 mouse mAb against SK-N-SH (1) cell lysate.
  • Flow cytometric analysis of K562 cells using ALK/p80 mouse mAb (green) and negative control (red).
  • Immunohistochemical analysis of paraffin-embedded human bladder cancer tissues using ALK/p80 mouse mAb with DAB staining.
  • Immunohistochemical analysis of paraffin-embedded human stomach tissues using ALK/p80 mouse mAb with DAB staining.

图片

  • fff
    Elisa

    Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

  • fff
    Western Blot

    Western blot analysis using ALK/p80 mouse mAb against SK-N-SH (1) cell lysate.

  • fff
    Flow cytometric

    Flow cytometric analysis of K562 cells using ALK/p80 mouse mAb (green) and negative control (red).

  • fff
    Immunohistochemistry

    Immunohistochemical analysis of paraffin-embedded human bladder cancer tissues using ALK/p80 mouse mAb with DAB staining.

  • fff
    Immunohistochemistry

    Immunohistochemical analysis of paraffin-embedded human stomach tissues using ALK/p80 mouse mAb with DAB staining.

Mouse Antibody to ALK/p80
Catalog#   :  32089
Size/Concentration： 50ul100ul
Price:￥ 12802180
Instruction:
Specification
Entrez GeneID238
AliasesCD246; NBLST3
Clone#8C9A2
MW176.4kDa
Host/IsotypeMouse IgG1
Storage4℃; -20℃ for long term storage. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenPurified recombinant fragment of human ALK/p80 (AA: 1359-1460) expressed in E. Coli.
FormulationPurified antibody in PBS with 0.05% sodium azide
Application
ELISA1/10000
WB1/500 - 1/2000
FCM1/200 - 1/400
IHC1/200 - 1/1000
Description

This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain. It plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system. This gene has been found to be rearranged, mutated, or amplified in a series of tumours including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumourigenesis, including ALK (chromosome 2)/EML4 (chromosome 2), ALK/RANBP2 (chromosome 2), ALK/ATIC (chromosome 2), ALK/TFG (chromosome 3), ALK/NPM1 (chromosome 5), ALK/SQSTM1 (chromosome 5), ALK/KIF5B (chromosome 10), ALK/CLTC (chromosome 17), ALK/TPM4 (chromosome 19), and ALK/MSN (chromosome X).

References
1.BMC Cancer. 2020 May 27;20(1):479.
2.Pathol Res Pract. 2019 Dec;215(12):152669.
Sequence

1359-1460


Diagram
Elisa

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western Blot

Western blot analysis using ALK/p80 mouse mAb against SK-N-SH (1) cell lysate.

Flow cytometric

Flow cytometric analysis of K562 cells using ALK/p80 mouse mAb (green) and negative control (red).

 

Immunohistochemistry

Immunohistochemical analysis of paraffin-embedded human bladder cancer tissues using ALK/p80 mouse mAb with DAB staining.

Immunohistochemistry

Immunohistochemical analysis of paraffin-embedded human stomach tissues using ALK/p80 mouse mAb with DAB staining.

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