S100A6
图片
- Immunohistochemistry
Immunohistochemical analysis of paraffin-embedded human brain glioma tissue showing nuclear localization using calcyclin mouse mAb with DAB staining.
Mouse Antibody to S100A6
Catalog#
: 20054
| Size/Concentration： | 50ul | 100μl | |
| Price:￥ | 1280 | 2180 |
Instruction: 
Specification
| Entrez GeneID | 6277 |
| Aliases | S100A6; 2A9; PRA; 5B10; CABP; CACY |
| Clone# | 7D11 |
| Host/Isotype | Mouse IgG1 |
| Storage | 4℃; -20℃ for long term storage. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of calcyclin expressed in E. Coli. |
| Formulation | Purified antibody in PBS containing 0.03% sodium azide. |
Application
| ELISA | 1/10000 |
| IHC | 1/200 - 1/1000 |
Description
Calcyclin encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.
References
1. Bean C.et.al J Mol Biol. 2005 Jun 3;349(2):349-66.
2. HWang R.et.al J Biol Chem. 2004 May 14;279(20):21239-47.
2. HWang R.et.al J Biol Chem. 2004 May 14;279(20):21239-47.
Sequence
20-90
Diagram
| Immunohistochemistry |
Immunohistochemical analysis of paraffin-embedded human brain glioma tissue showing nuclear localization using calcyclin mouse mAb with DAB staining. |