Specification
Entrez GeneID | 3576 |
Aliases | IL8 |
Clone# | 3E4D8 |
Host/Isotype | Mouse IgG1 kappa |
Storage | 4℃; -20℃ for long term storage. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human IL-8 expressed in E. Coli. |
Formulation | Ascitic fluid containing 0.03% sodium azide. |
Application
ELISA | 1/10000 |
Description
Interleukin-8 (IL-8) is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. IL-8 is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. IL-8 and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q.
References
1. Baggiolini M. et al. 1991. FEBS Lett. 307:97-101.
2. Mukaida N. et al. 1989. J.Immunol.143:1366-1371.
2. Mukaida N. et al. 1989. J.Immunol.143:1366-1371.
Diagram