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CD126

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
  • Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
  • Western blot analysis using CD126 mouse mAb against Jurkat (1), MOLT4 (2),Raw264.7 (3) and THP-1 (4) cell lysate.
  • Flow cytometric analysis of Jurkat cells using CD126 mouse mAb (green) and negative control (red).
  • Flow cytometric analysis of K562 cells using CD126 mouse mAb (green) and negative control (red).
  • Flow cytometric analysis of THP-1 cells using CD126 mouse mAb (green) and negative control (red).
  • Flow cytometric analysis of U937 cells using CD126 mouse mAb (green) and negative control (red).

图片

  • Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

  • Western blot analysis using CD126 mouse mAb against Jurkat (1), MOLT4 (2),Raw264.7 (3) and THP-1 (4) cell lysate.

  • Flow cytometric analysis of Jurkat cells using CD126 mouse mAb (green) and negative control (red).

  • Flow cytometric analysis of K562 cells using CD126 mouse mAb (green) and negative control (red).

  • Flow cytometric analysis of THP-1 cells using CD126 mouse mAb (green) and negative control (red).

  • Flow cytometric analysis of U937 cells using CD126 mouse mAb (green) and negative control (red).

Mouse Antibody to CD126
Catalog#   :  32240
Size/Concentration: 50ul100ul
Price: 12802180
Instruction:
Specification
Entrez GeneID3570
AliasesIL6Q; gp80; CD126; HIES5; IL-6R; IL6RA; IL6RQ; IL-1Ra; IL-6RA; IL6QTL; IL-6R-1
Clone#4A7B2
MW52kDa
Host/IsotypeMouse IgG1
Storage4℃; -20℃ for long term storage. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenPurified recombinant fragment of human CD126 (AA:EXTRA 20-177) expressed in E. Coli.
FormulationPurified antibody in PBS with 0.05% sodium azide
Application
ELISA1/10000
WB1/500 - 1/2000
FCM1/200 - 1/400
Description

This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been identified in this gene. A pseudogene of this gene is found on chromosome 9. [provided by RefSeq, Aug 2020]

References
1.Medicine (Baltimore).2020 Dec 11;99(50):e23659.
2.Biomed Res Int.2021 Jan 28;2021:2615059.

Diagram
Elisa

Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western Blot

Western blot analysis using CD126 mouse mAb against Jurkat (1), MOLT4 (2),Raw264.7 (3) and THP-1 (4) cell lysate.

Flow cytometric

Flow cytometric analysis of Jurkat cells using CD126 mouse mAb (green) and negative control (red).

 

Flow cytometric

Flow cytometric analysis of K562 cells using CD126 mouse mAb (green) and negative control (red).

Flow cytometric

Flow cytometric analysis of THP-1 cells using CD126 mouse mAb (green) and negative control (red).

Flow cytometric

Flow cytometric analysis of U937 cells using CD126 mouse mAb (green) and negative control (red).

 

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