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EphA1

Western blot analysis using EphA1 mouse mAb against A549 (1) and Hela (2) cell lysate.
  • Western blot analysis using EphA1 mouse mAb against A549 (1) and Hela (2) cell lysate.
  • Immunohistochemical analysis of paraffin-embedded human ovary carcinoma (left) and breast carcinoma (right), showing cytoplasmic localization using EphA1 mouse mAb with DAB staining.

图片

  • Western blot analysis using EphA1 mouse mAb against A549 (1) and Hela (2) cell lysate.

  • Immunohistochemical analysis of paraffin-embedded human ovary carcinoma (left) and breast carcinoma (right), showing cytoplasmic localization using EphA1 mouse mAb with DAB staining.

Mouse Antibody to EphA1
Catalog#   :  20053
Size/Concentration: 50ul100μl
Price: 12802180
Instruction:
Specification
Entrez GeneID2041
AliasesEPH; EPHT; EPHT1
Clone#5D2
MW108kDa
Host/IsotypeMouse IgG1
Storage4℃; -20℃ for long term storage. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenPurified recombinant fragment of EphA1 expressed in E. Coli.
FormulationPurified antibody in PBS containing 0.03% sodium azide.
Application
ELISA1/10000
WB1/500 - 1/2000
IHC1/200 - 1/1000
Description
EPH receptor A1 (EphA1), with 976-amino acid protein(about 107 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date and their ligands, the ephrins,can be subdivided into two major subclasses, ephrin-A and ephrin-B. Interaction of Eph receptor tyrosine kinases with their membrane bound ephrin ligands initiates bidirectional signaling events that regulate cell migratory and adhesive behavior, particularly in the nervous system. They have been implicated in various developmental processes, including axonal guidance, angiogenesis, morphogenesis and carcinogenesis.
References
1. Shannon L. Duffy, Kirsten A. Steiner, Patrick P.L. Tam Gene Expr Patterns. 2006 Feb 6.
2. Elena B. Pasquale. Nat Rev Mol Cell Biol.2005 Jun; 6(6): 462-75.
Sequence

38-144


Diagram
Western Blot

Western blot analysis using EphA1 mouse mAb against A549 (1) and Hela (2) cell lysate.

Immunohistochemistry

Immunohistochemical analysis of paraffin-embedded human ovary carcinoma (left) and breast carcinoma (right), showing cytoplasmic localization using EphA1 mouse mAb with DAB staining.

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