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Foxp3

Confocal Immunofluorescence analysis of PANC-1 cells using FOXP3 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
  • Confocal Immunofluorescence analysis of PANC-1 cells using FOXP3 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
  • Immunohistochemical analysis of paraffin-embedded human lymphocyto tissue, showing cytoplasmic and nuclear localization using Foxp3 mouse mAb with DAB staining.

图片

  • Confocal Immunofluorescence analysis of PANC-1 cells using FOXP3 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

  • Immunohistochemical analysis of paraffin-embedded human lymphocyto tissue, showing cytoplasmic and nuclear localization using Foxp3 mouse mAb with DAB staining.

Mouse Antibody to Foxp3
Catalog#   :  20045
Size/Concentration: 50ul100μl
Price: 12802180
Instruction:
Specification
Entrez GeneID50943
AliasesJM2; AIID; IPEX; PIDX; XPID; DIETER, Foxp3
Clone#2A11G9; 2A11C2
Storage4℃; -20℃ for long term storage. Avoid freeze/thaw cycles.
Species ReactivityHuman,Mouse
ImmunogenPurified recombinant fragment of human Foxp3 expressed in E. Coli.
FormulationAscitic fluid containing 0.03% sodium azide.
Application
ELISA1/10000
ICC1/200 - 1/1000
IHC1/200 - 1/1000
Description
The transcription factor Foxp family includes Foxp1, Foxp2, and Foxp3. The Foxp3 (50KDa)plays a key role in CD4(+) CD25(+) regulatory T cell function and represents a specific marker for these cells. Despite its strong association with regulatory T cell function, in humans little is known about the frequency of CD4(+) CD25(+) cells that express FOXP3 protein nor the distribution of these cells in vivo. FOXP3 may be a master regulatory gene and a more specific marker of regulatory T cells than other T cells.
References
1. Roncador G et al. Eur J Immunol. 2005. 35:1681-1691.
2. Yisong YW. PNAS. 2005 102 (14): 5126-5131.
Sequence

2-193


Diagram
Immunofluorescence

Confocal Immunofluorescence analysis of PANC-1 cells using FOXP3 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

Immunohistochemistry

Immunohistochemical analysis of paraffin-embedded human lymphocyto tissue, showing cytoplasmic and nuclear localization using Foxp3 mouse mAb with DAB staining.

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