Specification
Clone# | 2H2C4 |
Host/Isotype | Mouse IgG1 |
Storage | 4℃; -20℃ for long term storage. Avoid freeze/thaw cycles. |
Species Reactivity | Human Coronavirus |
Immunogen | Purified recombinant fragment of SARS-m protein expressed in E. Coli. |
Formulation | Subclonal supernatant. |
Application
ELISA | 1/10000 |
Description
SARS (severe acute respiratory syndrome) is caused by a human coronavirus. Human coronaviruses are the major cause of upper respiratory tract illness, such as the common cold, in humans. Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The complete sequence of the SARS virus release the coronavirus contains 25 open reading frames. SARS-m is a membrane (M) protein which plays a the key player in virion assembly. One of its functions is to mediate the incorporation of the spikes into the viral envelope.
References
1. Fournel S, Cell Immunol 1993 Aug; 150(1):194-204.
2. J. Virol., Sep 1999; 73: 7441 - 7452.
2. J. Virol., Sep 1999; 73: 7441 - 7452.
Diagram