Specification
Swissprot | Q07654 |
Gene Accession | BC017859 |
Aliases | ITF; P1B; TFI |
Host/Isotype | Immunogen-specific rabbit IgG |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Fusion protein of human TFF3 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Application
ELISA | 1/2000-1/5000 |
IHC | 1/50-1/200 |
Description
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. This gene is expressed in goblet cells of the intestines and colon. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.
Diagram
Immunohistochemistry |
The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P00025(TFF3 Antibody) at dilution 1/50. (Original magnification: ×200) |